منابع مشابه
T Memory Cells: Quality not Quantity
Immunological memory to pathogens is associated with clonal expansion and heightened responsiveness of antigen-specific T cells. Recent work emphasizes that, for efficient protective immunity, qualitative changes in T memory cells are vitally important.
متن کاملQuality not quantity: the pufferfish genome.
The genome of the pufferfish, Fugu rubripes (Fugu) is compact. With a similar gene complement to mammals and a genome size of just 400 Mb, gene density is high averaging one every 6-7 kb. Initial characterization of this genome has shown that although genes are much smaller and more densely spaced, their intron/exon structure is conserved with the resulting introns being small. There is little ...
متن کاملQuantity, not quality, of antibody response decreased in the elderly.
The burden of disease during seasonal influenza epidemics is felt most keenly among the very young and the elderly. Although vaccination effectively protects children and young adults against infection, it has limited efficacy in elderly individuals. This has been linked to a reduced ability to induce a robust serum antibody response. In this issue of the JCI, Sasaki et al. identify some of the...
متن کاملAnd, not or: Quality, quantity in scientific publishing
Scientists often perceive a trade-off between quantity and quality in scientific publishing: finite amounts of time and effort can be spent to produce few high-quality papers or subdivided to produce many papers of lower quality. Despite this perception, previous studies have indicated the opposite relationship, in which productivity (publishing more papers) is associated with increased paper q...
متن کاملLiving with pulmonary hypertension: quality not just quantity.
P ulmonary arterial hypertension (PAH) is a rare disease characterised by progressive right heart failure and premature death with a median survival prior to the availability of effective treatments of ,3 yrs [1, 2]. There has been significant progress in its management over the last two decades with the introduction of three classes of targeted therapies: prostanoids, endothelin-1 receptor ant...
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ژورنال
عنوان ژورنال: Science
سال: 2011
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.333.6040.268-d